The Second World Congress on Targeting Extracellular Vesicles (EVs) is scheduled for 15–16 October 2025 in Valencia, Spain. This landmark event, co-organized by the World Mitochondria Society and the International Society of Microbiota, will spotlight the rapidly evolving science where mitochondrial biology and microbiome research intersect via extracellular vesicles. Under the theme "Bridging Two Frontiers: Mitochondria & Microbiota", this edition aims to accelerate scientific discovery and clinical translation by bringing together world leaders in EV biology, mitochondrial medicine, microbiota research, and biotechnology. Extracellular vesicles are increasingly recognized as core messengers in intercellular communication and hold immense therapeutic promise. EVs can transport nucleic acids, proteins, lipids, and even mitochondrial components, enabling remote modulation of cellular states. "Extracellular vesicles are rewriting how we think about communication ins...