Scientists turn “junk DNA” into a powerful weapon against cancer

International Research Awards

Scientists turn “junk DNA” into a powerful weapon against cancer

The study, published in Blood, focused on two blood cancers: myelodysplastic syndrome (MDS) and chronic lymphocytic leukemia (CLL). These diseases often involve mutations in two key genes, ASXL1 and EZH2. Normally, these genes help regulate which other genes are active or inactive, maintaining proper cell function. When ASXL1 and EZH2 are damaged, this control breaks down, leading to unchecked cell production and cancer development.

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