How Fat Cells Help Cancer Outsmart Immune Warriors

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Scientists have uncovered a surprising ally that helps cancer evade the body’s immune system — fat cells. New research reveals that adipocytes (fat cells) release molecules that reprogram immune cells, weakening their ability to attack tumors. This “metabolic manipulation” allows cancer cells to hide from immune surveillance and resist immunotherapy treatments. Understanding how fat tissue fuels this immune evasion could open doors to novel therapies that target the tumor microenvironment and restore the body’s natural defenses against cancer.

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