165,000 dementia patients reveal hidden stroke risk from common drug

 165,000 dementia patients reveal hidden stroke risk from common drug

A massive UK study of more than 165,000 dementia patients has uncovered troubling new evidence about risperidone, a commonly used drug for severe agitation. Researchers found the antipsychotic increases stroke risk in dementia patients across the board—including those with no prior heart disease or stroke—challenging the long-held belief that some patients might be safer candidates than others. Because risperidone is the only drug of its type licensed for dementia, doctors often use it as a last resort when distressing symptoms become unmanageable.

A huge UK study suggests risperidone may raise stroke risk for all dementia patients—leaving doctors with no clearly “safe” group. 
A large UK study involving more than 165,000 people with dementia has found that the drug risperidone is linked to a higher risk of stroke in all groups of patients. The findings challenge previous assumptions that certain patients might be safer candidates for the medication. Instead, researchers found no clearly "safe" group.


Risperidone is a powerful antipsychotic often prescribed to dementia patients who experience severe agitation or aggressive behavior. It is commonly used in care homes when non drug approaches fail to control distressing symptoms.

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